Pfizer Drug Depletion Studies

      The objective of this study is to measure the Fipronil residues in bovine milk from lactating dairy cows at various withdrawal times following topical administration of Fipronil @1.0 mg/Kg in order to define the residue depletion profile. Fipronil, an acaricide can be used to prevent, control and treat the tick infestation in the dairy farms. A total of 15 Jersey Sahiwal crossbred cows of second parity in fourth month of lactation cycle of Department of Livestock Production Management, College of Veterinary Science, Tirupati were utilized for the study purpose. No signs of illness or infection especially mastitis and milk sample from the animals will be checked for SCC (<400,000 in the composite 4-quarter milk sample, prior to start of the study.